ECOCAPTURE for the Assessment of Apathy Under Real-life Conditions

Registry record from ClinicalTrials.gov (NCT04865172). This is a study registration, not published results. Lead sponsor: Institut National de la Santé Et de la Recherche Médicale, France. Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 44 participants (ACTUAL). Conditions: Frontotemporal Dementia, Behavioral Variant, Alzheimer Disease. Interventions: OTHER: Remote collection of passive and active data for 28 consecutive days. Primary outcome measures: Acceleration (in g) , 28 days; Electrodermal activity (in microsiemens) , 28 days; Blood volume pulse (or relative blood flow) , 28 days; Bedtime and getting up time (Week 1) , once during the first week of the follow-up; Bedtime and getting up time (Week 2) , once during the second week of the follow-up; Bedtime and getting up time (Week 3) , once during the third week of the follow-up; Bedtime and getting up time (Week 4) , once during the fourth week of the follow-up; Meal times (Week 1) , once during the first week of the follow-up; Meal times (Week 2) , once during the second week of the follow-up; Meal times (Week 3) , once during the third week of the follow-up; Meal times (Week 4) , once during the fourth week of the follow-up; Autonomy for going to bed and getting up (Week 1) , once during the first week of the follow-up; Autonomy for going to bed and getting up (Week 2) , once during the second week of the follow-up; Autonomy for going to bed and getting up (Week 3) , once during the third week of the follow-up; Autonomy for going to bed and getting up (Week 4) , once during the fourth week of the follow-up; Signs of tiredness (Week 1) , once during the first week of the follow-up; Signs of tiredness (Week 2) , once during the second week of the follow-up; Signs of tiredness (Week 3) , once during the third week of the follow-up; Signs of tiredness (Week 4) , once during the fourth week of the follow-up; Involvement in the activities related to meal (Week 1) , once during the first week of the follow-up; Involvement in the activities related to meal (Week 2) , once during the second week of the follow-up; Involvement in the activities related to meal (Week 3) , once during the third week of the follow-up; Involvement in the activities related to meal (Week 4) , once during the fourth week of the follow-up; Usefulness of involvement in the activities related to meal (Week 1) , once during the first week of the follow-up; Usefulness of involvement in the activities related to meal (Week 2) , once during the second week of the follow-up; Usefulness of involvement in the activities related to meal (Week 3) , once during the third week of the follow-up; Usefulness of involvement in the activities related to meal (Week 4) , once during the fourth week of the follow-up; Autonomy of the involvement in the activities related to meal (Week 1) , once during the first week of the follow-up; Autonomy of the involvement in the activities related to meal (Week 2) , once during the second week of the follow-up; Autonomy of the involvement in the activities related to meal (Week 3) , once during the third week of the follow-up; Autonomy of the involvement in the activities related to meal (Week 4) , once during the fourth week of the follow-up; Quantity of interactions during meals (Week 1) , once during the first week of the follow-up; Quantity of interactions during meals (Week 2) , once during the second week of the follow-up; Quantity of interactions during meals (Week 3) , once during the third week of the follow-up; Quantity of interactions during meals (Week 4) , once during the fourth week of the follow-up; Quality of interactions during meals (Week 1) , once during the first week of the follow-up; Quality of interactions during meals (Week 2) , once during the second week of the follow-up; Quality of interactions during meals (Week 3) , once during the third week of the follow-up; Quality of interactions during meals (Week 4) , once during the fourth week of the follow-up. Brief summary: ECOCAPTURE@HOME is a study which is currently being developed with the objective to capture the behavioral signature of apathy in everyday life context through remote monitoring of participants' behavior for about one month. Participants will not only be patients with apathy but also their spouse caregiver. Behavioral markers of apathy will be extracted from a combination of: 1/ objective physiological data from sensors on a bracelet worn by participants; 2/ subjective data filled by the caregiver through an application. Thus investigators will collect a pool of metrics and show they can measure three assumed behavioral markers of apathy (daytime activity, quality of sleep and emotional arousal), which in turn allow to predict caregiver's perception of the dyad's psychological state. The final goal is to lay the foundations for the development of a clinical tool for the remote follow-up of patient-caregiver couples.