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Life sciences · Interventional Study
ClinicalTrials.gov · September 23, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT05183230). This is a study registration, not published results. Lead sponsor: Weill Medical College of Cornell University. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 115 participants (ESTIMATED). Conditions: Suicide, Attempted, Suicidal Ideation, Depression. Interventions: BEHAVIORAL: WellPATH-PREVENT; BEHAVIORAL: Optimized WellPATH-PREVENT. Primary outcome measures: Change in Event Related Potential - Late Positive Potential (ERP/LPP) - R61 , Study Entry, Week 6, Week 12; Change in Event Related Potential - Late Positive Potential (ERP/LPP) - R33 , Study Entry, Week 6, Week 12, Week 24; Change in Self-Reported Affect - R61 , Study Entry, Week 6, Week 12; Change in Self-Reported Affect - R33 , Study Entry, Week 6, Week 12, Week 24; Change in Emotion Regulation (Cognitive Reappraisal Subscale of ER Questionnaire) - R61 , Study Entry, Week 6, Week 12; Change in Emotion Regulation (Cognitive Reappraisal Subscale of ER Questionnaire) - R33 , Study Entry, Week 6, Week 12, Week 24; Change in Client Satisfaction with Treatment (CSQ) - R61 , Week 6, Week 12; Change in Client Satisfaction with Treatment (CSQ) - R33 , Week 6, Week 12, Week 24; Change in Suicide Risk - Columbia Suicide Severity Scale (C-SSRS) - R61 , Weekly from Study Entry to Week 12 (R61); Change in Suicide Risk - Columbia Suicide Severity Scale (C-SSRS) - R33 , Weekly from Study Entry to Week 24. Brief summary: The goal of this project is to test whether WellPATH-PREVENT (a novel, mobile psychosocial intervention) improves a specific aspect of emotion regulation, i.e., cognitive reappraisal ability, and reduces suicide risk in middle-aged and older adults (50-90 years old) who have been discharged after a suicide-related hospitalization (i.e. for suicidal ideation or suicide attempt).