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Life sciences · Interventional Study
ClinicalTrials.gov · November 5, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07346911). This is a study registration, not published results. Lead sponsor: University of Oslo. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 495 participants (ESTIMATED). Conditions: Major Depression Disorder, ANXIETY DISORDERS (or Anxiety and Phobic Neuroses). Interventions: BEHAVIORAL: Transdiagnostic app intervention; BEHAVIORAL: Transdiagnostic mastery course. Primary outcome measures: Relapse: Number of participants scoring above the diagnostic cut-off on the PHQ-9 modified for teens during the 12-month follow-up. , From enrollment to the end of follow-up at 12-months.; Time until relapse; reaching the diagnostic criteria of MDD according to PHQ-9 modified for teens , From enrollment to 12-months follow-up. Brief summary: Some adolescents experience periods of anxiety and/or depression, and some find that these periods return over time. The purpose of this study is to examine whether digital interventions-where individuals work systematically with their own thoughts and feelings during periods when they feel well-can help them maintain well-being for longer. The study includes adolescents aged 16-19 who have previously experienced episodes of depression and/or anxiety to a degree that led them to seek help (e.g., from a school nurse, general practitioner, health clinic, or child and adolescent mental health service). Through a research app on their smartphones, participants complete tasks and answer questionnaires. The study is fully digital. Some participants meet with a therapist in digital group sessions, while others work independently with the digital content. We will also examine the cost-benefit aspects of offering such interventions. If the study achieves its goals, digital interventions may eventually become a service offered to adolescents recovering from depression and anxiety.