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Life sciences · Interventional Study
ClinicalTrials.gov · September 30, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07850726). This is a study registration, not published results. Lead sponsor: Norwegian University of Science and Technology. Recruitment status: NOT_YET_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 25 participants (ESTIMATED). Conditions: Heart Failure. Interventions: BEHAVIORAL: Sustained Isometric Handgrip Exercise; BEHAVIORAL: Semi-Supine Bicycle Exercise. Primary outcome measures: Echocardiographic Acquisition Success , During one study visit: at rest, during the handgrip and bicycle test.. Brief summary: Noninvasive left ventricular pressure-strain loop analysis estimates myocardial work from longitudinal strain, brachial systolic blood pressure, and cardiac valve-event timing. It provides global work index, constructive work, wasted work, and work efficiency. This study evaluates a deep-learning method that automates myocardial work and loop-shape analysis. The method may reduce analysis time, improve reproducibility, and identify patterns associated with heart failure.