Life sciences · Preprint
arXiv · September 10, 2026
Raises a question worth testing. It does not answer one.
This is a theoretical computer science preprint establishing that optimal planning with multi-step lookahead in reinforcement learning is NP-hard across all fixed discount factors, and proposing a randomized polynomial-time approximation scheme. The work does not provide empirical validation, clinical evidence, or real-world performance data.
Preprint.
Exact planning with transition lookahead remains NP-hard for every fixed rational discount factor γ∈(0,1) A randomized polynomial-time approximation scheme is introduced for every fixed lookahead depth ℓ Cumulative regret leading term matches classical tabular discounted RL up to logarithmic factors
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The source did not state who this applies to in practice.
This is a theoretical computer science contribution proving computational hardness and proposing algorithmic schemes, with no empirical validation or clinical/translational data.
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We study reinforcement learning (RL) with transition look-ahead, where the agent may observe which states would be visited upon playing any sequence of $\ell$ actions before deciding its course of action. Although look-ahead can substantially improve achievable performance, it is known that optimal planning with multi-step transition look-ahead is NP-hard, but this hardness was established using discount factors arbitrarily close to one. It was therefore unknown whether the problem remains hard for any discount factor, and whether near-optimal planning can nevertheless be performed efficiently. We resolve both questions. First, we show that for every fixed rational discount factor ($γ\in(0,1)$), exact planning remains NP-hard. Second, we introduce a randomized polynomial-time approximation scheme for every fixed look-ahead depth. We then extend our approach to unknown transitions and stochastic rewards using optimism and variance-adaptive confidence bounds. The resulting algorithm achieves cumulative regret whose leading term matches classical tabular discounted RL up to logarithmic factors. Thus, although exact planning with transition look-ahead is NP-hard, efficient near-optimal planning and learning remain possible.
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