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Frontotemporal Dementia / Alzheimer Disease / Neurodegenerative Diseases · Observational Study
ClinicalTrials.gov · August 10, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a registry record documenting a planned retrospective register-linkage study examining the association between criminal behaviour, sociodemographic factors, and neurodegenerative disease diagnosis across eleven conditions in Finland. No results are yet reported. The study is actively recruiting and uses national register data spanning 1987–2021 with matched population controls.
Observational. Neurodegenerative Diseases, Alzheimer Disease, Frontotemporal Dementia, Lewy Body Disease, Vascular Dementia, Parkinson Disease, Progressive Supranuclear Palsy…. Intervention: Patients with neurodegenerative disease; Matched controls. Compared with: Matched population controls (10 per case), matched on age, sex, and geographical area. n = 61,292. 1 site: Finland.
This is a registry record documenting a planned retrospective register-linkage study examining the association between criminal behaviour, sociodemographic factors, and neurodegenerative disease diagnosis across eleven conditions in Finland. No results are yet reported. The study is actively recruiting and uses national register data spanning 1987–2021 with matched population controls.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
When completed and reported, this study may establish whether criminal or disruptive behaviour precedes diagnosis of neurodegenerative disease and whether sociodemographic trajectories change peridiagnostically. Results could inform early recognition strategies and inform understanding of disease-related behavioural change phenotypes. At present, no conclusions can be drawn.
This is a registry record for a planned retrospective observational study with no results reported; it describes methodology and enrollment targets only.
As stated by the source record.
Quoted from the source exactly as published.
When completed and reported, this study may establish whether criminal or disruptive behaviour precedes diagnosis of neurodegenerative disease and whether sociodemographic trajectories change peridiagnostically. Results could inform early recognition strategies and inform understanding of disease-related behavioural change phenotypes. At present, no conclusions can be drawn.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT06209515). This is a study registration, not published results. Lead sponsor: Kuopio University Hospital. Recruitment status: ACTIVE_NOT_RECRUITING. Study type: OBSERVATIONAL. Enrollment: 61292 participants (ESTIMATED). Conditions: Neurodegenerative Diseases, Alzheimer Disease, Frontotemporal Dementia, Lewy Body Disease, Vascular Dementia, Parkinson Disease, Progressive Supranuclear Palsy, Corticobasal Degeneration, Multiple System Atrophy, Amyotrophic Lateral Sclerosis, Huntington Disease. Primary outcome measures: Criminal behaviour: Type of offence, time of offence and other disruptive behaviour , 1996-2020; Socio-demographic data , 1987-2021; Hospital diagnoses , 1994-2021; Medication use , 1995-2021; Causes of death , 2010-2021. Brief summary: In this retrospective register study, clinically classified individuals with neurodegenerative disease from the years 2010-2021 will be verified from the clinical records from KUH and Oulu University Hospital (OUH). Based on the Finnish social security number, these individuals will be linked to the the national registers of Statistics Finland and Finnish Social and Health Data Permit Authority Findata including incomes, sociodemographic factors, education, occupation, criminal records as well as to the national registers including the bought pharmaceuticals, comorbidities and causes of death. For each study case, 10 randomly selected control cases, matched with age, sex and geographical area, will be used. The aim of the study is to examine: * 1\) The prevalence of criminal and other disruptive behaviour in groups of different neurodegenerative diseases prior to and after the diagnosis * 2\) Changes in employment, residency,income, and marital status prior to and after the neurodegenerative disease diagnosis * 3\) Hospital diagnoses and reimbursable drugs prior to and after the diagnosis * 4\) Causes of death in patients with neurodegenerative disease to study excess mortality of the patients
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