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Life sciences · Interventional Study
ClinicalTrials.gov · October 26, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Interventional Study.
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Registry record from ClinicalTrials.gov (NCT05342077). This is a study registration, not published results. Lead sponsor: University of California, Los Angeles. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 59 participants (ACTUAL). Conditions: Positive Affect, Depression. Interventions: BEHAVIORAL: Virtual Reality-Reward Training (VR-RT); BEHAVIORAL: Virtual Reality-Memory Training (VR-MT). Primary outcome measures: Depression, Anxiety, and Stress Scales (DASS-21) , Change from baseline to follow-up (Week 12); The Positive Affect and Negative Affect Schedule-Expanded Form (PANAS X) (General Dimensions Scales) , Change from baseline to follow-up (Week 12); MASQ-AD 14 Item , Change from baseline to follow-up (Week 12). Brief summary: The purpose of this study is to compare the effects of Virtual Reality-Reward Training (VR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect and other clinical symptoms. VR-Reward Training is a novel intervention aimed at enhancing savoring of positive experiences among individuals with depression and low positive affect through guided imaginal recounting following immersion in positive VR experiences. Target enrollment is 80 male and female participants with low positive affect, depression, and impaired functioning, who are at least 18 years old, who will be randomly assigned to 7 weeks of either Virtual Reality-Reward Training (VR-RT) or Virtual Reality-Memory Training (VR-MT). Participants will complete in-person VR sessions, laboratory assessments, self-report questionnaires as part of the study. The total length of participation is around 3 months.