Loading
Life sciences · Journal article
Nano Today · September 15, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Journal article.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
What is missing. This record has no bottom line, key findings, reported figures, evidence dimensions. That is a gap in the analysis, not a judgement about the study.
Amino acid metabolism occupies a central position in tumor biology and cancer therapy. Amino acids are not only fundamental substrates for protein synthesis but also critical metabolic and signaling hubs that regulate energy production, nucleotide biosynthesis, redox homeostasis, and epigenetic programming. Owing to their indispensable roles in bioenergetics, anabolic support, and cellular homeostatic control, amino acid metabolism has become a major focus of contemporary cancer research and targeted intervention. However, despite the therapeutic promise of targeting these metabolic vulnerabilities, clinical translation falters due to poor bioavailability and rapid adaptive rewiring. Nanotechnology bridges this gap by offering precision tools to enhance antitumor efficacy while reducing systemic toxicity: by leveraging tumor-specific amino acid metabolic profiles, nanomedicines with targeted delivery and controllable release can be engineered to increase intratumoral drug exposure, minimize off-target effects, and improve therapeutic outcomes. This review systematically integrates the biological dysregulation of specific amino acids with recent progress in nanomedicine strategies. We discuss biological mechanisms and therapeutic engineering side-by-side for key amino acids, and analyze the major challenges limiting clinical translation, outlining potential directions for future optimization.