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Life sciences · Interventional Study
ClinicalTrials.gov · October 6, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07584239). This is a study registration, not published results. Lead sponsor: Ohio State University Comprehensive Cancer Center. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 30 participants (ESTIMATED). Conditions: Resectable Lung Non-Small Cell Carcinoma. Interventions: PROCEDURE: Biospecimen Collection; OTHER: Exercise Intervention; OTHER: Exercise Intervention; OTHER: Exercise Intervention; OTHER: Internet-Based Intervention; PROCEDURE: Physical Therapy; BEHAVIORAL: Relaxation Technique; OTHER: Survey Administration; OTHER: Text Message-Based Navigation Intervention. Primary outcome measures: Adherence (feasibility) , At 12 week follow up session; Retention (feasibility) , Up to 6 months post recruitment. Brief summary: This clinical trial tests two different physical therapy and relaxation interventions, one in-person and at-home called Resiliency and Operative Success for Adults Receiving Lung Cancer Surgery (ROAR-LCS) and one virtually called BeFitMe. These programs that take place before and after standard of care lung cancer surgery, called prehabilitation programs, promote resiliency and patient outcomes (operative success) for adults receiving lung cancer surgery. Lung cancers occur in the chest and often cause symptoms for patients. Poor physical performance and negative mood are two risk factors for a decline in functional status after surgery. Physical therapy and relaxation interventions (i.e. progressive muscle relaxation) are two such interventions that may improve physical and emotional recovery including a potential shortened hospital stay for patients receiving surgery for lung cancer. Starting these intervention programs early alongside cancer treatment can improve symptoms, improve functional status and quality of life, help with emotional needs of patients, improve recovery time, and may even prolong life. ROAR-LCS and BeFitMe may promote resiliency and operative success for adults receiving lung cancer surgery.