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Life sciences · Observational Study
ClinicalTrials.gov · September 25, 2026
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Observational Study.
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Registry record from ClinicalTrials.gov (NCT00869817). This is a study registration, not published results. Lead sponsor: Washington University School of Medicine. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 700 participants (ESTIMATED). Conditions: Alzheimer's Disease. Primary outcome measures: Positive predictive power of a biomarker or group of biomarkers , Variable follow-up assessment based on age in relation to age at onset of affected parent.; Biomarkers obtained by blood draw, lumbar puncture, MRI, FDG PET, PET amyloid imaging , Variable follow-up assessment based on age in relation to age at onset of affected parent; Clinical markers also examined from clinical interview and cognitive testing , Variable follow-up assessment based on age in relation to age at onset of affected parent. Brief summary: The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.