Life sciences · Preprint
arXiv · September 8, 2026
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This is a mathematical and statistical methods paper proposing a two-step procedure for scalar-on-function linear regression from noisy discretized functional data. The authors establish theoretical convergence rates and minimax optimality under regularity assumptions, with illustration on simulated and meteorological data, but provide no clinical validation, comparative efficacy, or evidence of practical advantage.
Preprint.
Oracle-type inequalities established for prediction error with respect to reconstructed and true latent curves Convergence rates derived showing minimax optimality when number of grid points is sufficiently large Method illustrated on simulated data and one real meteorological dataset
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This is a methodological paper proposing a statistical estimation procedure with theoretical analysis but no clinical application, comparative validation, or empirical performance benchmarking against existing methods.
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In this paper, we consider the scalar-on-function linear regression model under a realistic sampling scheme in which the functional covariates are observed on a regular grid and contaminated by additive noise. We propose a two-step estimation procedure: first, the underlying curves are reconstructed from the discrete noisy observations using a Fourier-based projection method; second, the slope function is estimated by a penalized least-squares criterion over finite-dimensional trigonometric spaces, with data-driven selection of the model dimension. We establish oracle-type inequalities for the prediction error, both with respect to the reconstructed curves and to the true latent curves. Under regularity assumptions on the slope function and polynomial decay of the eigenvalues of the covariate, we derive convergence rates for the prediction error and show that our estimator attains the minimax rate when the number of grid points is sufficiently large. Finally, the proposed method is illustrated on simulated data and on a real meteorological dataset.
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