Obestity / Healthy Volunteer · Observational Study

Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism

ClinicalTrials.gov · August 11, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a planned observational study registered but not yet recruiting, designed to explore associations between perceptions of unpredictability during childhood and objective measures of food consumption and metabolic markers in healthy adults aged 18–60 years. No results are currently reported in this registry record.

What was studied

Observational. Healthy Volunteer, Obestity; age from 18 Years; to 60 Years. Intervention: Healthy Volunteer. n = 110. 1 site: United States.

Key findings

Safety

Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.

Who this may help

The source did not state who this applies to in practice.

Plain-language summary

This is a planned observational study with no results yet reported; it describes the protocol and design for investigating associations between childhood unpredictability perceptions and adult eating behaviours using objective measures.

Study design

As stated by the source record.

MethodsCohort model. Prospective time perspective. Primary outcome measures: To determine whether an association exists between unpredictability schema measures and ad libitum food intake. (assessed at Day 10); To determine whether an association exists between the unpredictability schema and experience scores and eating in the absence of hunger (assessed at Day 10)

DesignObservational

PopulationHealthy Volunteer, Obestity; age from 18 Years; to 60 Years

Sample size110

InterventionHealthy Volunteer

Setting1 site: United States

Reported figures

Quoted from the source exactly as published.

Planned enrollment110

Primary outcome measure 1Association between unpredictability schema measures and ad libitum food intake (Day 10)

Primary outcome measure 2Association between unpredictability schema and experience scores and eating in the absence of hunger (Day 10)

Caveats

This is a study registration with recruitment not yet started; no results, outcome data, or effect sizes are reported.
Study is observational with no control group; causality cannot be inferred.
Population eligibility criteria and recruitment setting details are not fully specified in the registry record.
Sample size calculation and statistical power are not documented in the registry record.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

moderate

Observational natural history study with structured assessments; no randomization or control group.

Directness

moderate

Directly measures ad libitum food intake and eating in absence of hunger; also collects objective metabolic data.

Consistency

insufficient

No results reported; consistency cannot be assessed from registry record alone.

Risk of bias

insufficient

Registry describes protocol only; risk of bias assessment requires outcome data and methodological detail.

Sample adequacy

limited

Planned enrollment 110 participants; adequacy depends on effect size and outcome variance, not yet known.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT06690294). This is a study registration, not published results. Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Recruitment status: NOT_YET_RECRUITING. Study type: OBSERVATIONAL. Enrollment: 110 participants (ESTIMATED). Conditions: Healthy Volunteer, Obestity. Primary outcome measures: To determine whether an association exists between unpredictability schema measures and ad libitum food intake. , Day 10; To determine whether an association exists between the unpredictability schema and experience scores and eating in the absence of hunger , Day 10. Brief summary: Background: Many people in the United States are overweight or obese. This natural history study will look into how life events during childhood can impact eating behaviors and weight gain as adults. Objective: To explore how childhood experiences affect adult eating behaviors. Eligibility: Healthy people aged 18 to 60 years. Design: Participants will have 3 clinic visits. They will be screened with blood tests. They will answer questions about their alcohol and tobacco use. At the next visit, participants will undergo these activities: Parts of their body (such as waist, neck, and thighs) will be measured with a tape. They will have an imaging scan to find out how much body fat they have. They will start wearing a device like a wristwatch that measures their physical activity. They will wear this device for up to 10 days. They will wear a device on their upper arm or belly that measures blood glucose (sugar) levels. Participants will wear this for 7-10 days. They will answer questions about their education, childhood, and routines. They will receive a kit to collect a stool sample at home. At the last visit, participants will have these tests: Participants will relax and breathe normally while wearing a clear, plastic canopy that fits over their entire head. Blood samples will be taken before and after participants drink a sugary drink. Participants will be offered a large selection of foods for lunch. They will eat as much as they want. Then they will answer questions about how they feel about food and themselves.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

NCT06690294National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)ObestityHealthy Volunteer