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Invasive Breast Carcinoma / Petrolatum-Mineral Oil-Lanolin-Ceresin Ointment / Breast Ductal Carcinoma in Situ · Phase 1 Trial
ClinicalTrials.gov · August 17, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a registry record for a Phase 1 trial comparing Aquaphor (petrolatum-based) and Miaderm (water-based cream with calendula, hyaluronate, aloe vera) for acute radiation dermatitis in breast cancer patients undergoing external beam radiation therapy. No results are posted in this registry record; the study remains active and not yet recruiting or completed.
Phase 1, Interventional, Randomized, Parallel, Open label, Supportive Care purpose. Breast Ductal Carcinoma In Situ, Invasive Breast Carcinoma; Female; age from 18 Years. Intervention: Arm I (Aquaphor); Arm II (Miaderm). Compared with: Aquaphor (petrolatum-based multi-purpose ointment). n = 208. 1 site: United States.
This is a registry record for a Phase 1 trial comparing Aquaphor (petrolatum-based) and Miaderm (water-based cream with calendula, hyaluronate, aloe vera) for acute radiation dermatitis in breast cancer patients undergoing external beam radiation therapy. No results are posted in this registry record; the study remains active and not yet recruiting or completed.
This is a registry record only; no efficacy or safety results are reported.
The source did not state who this applies to in practice.
This is a registry record of an active Phase 1 interventional trial with no results posted; the study design and planned enrollment are documented but outcomes remain unreported.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT05340673). This is a study registration, not published results. Lead sponsor: City of Hope Medical Center. Recruitment status: ACTIVE_NOT_RECRUITING. Phase: PHASE1. Study type: INTERVENTIONAL. Enrollment: 208 participants (ACTUAL). Conditions: Breast Ductal Carcinoma In Situ, Invasive Breast Carcinoma. Interventions: DRUG: Agent Affecting Integumentary System; OTHER: Petrolatum-Mineral Oil-Lanolin-Ceresin Ointment; OTHER: Quality-of-Life Assessment; OTHER: Questionnaire Administration. Primary outcome measures: Acute Radiation Dermatitis , Up to 120 days after completion of radiation therapy. Brief summary: This clinical trial compares two supplemental topical agents (Aquaphor and Miaderm) for the treatment of acute radiation dermatitis in patients with breast cancer undergoing radiation therapy. Radiation dermatitis is a radiation-induced skin reaction which can cause itching, swelling, pain, and general discomfort. Aquaphor is a commonly available, inexpensive, petrolatum-based multi-purpose ointment designed to protect and sooth extremely dry skin, chapped lips, cracked hands and feet, minor cuts and burns, and many other skin irritations. Miaderm is a water-based cream and contains ingredients like calendula, hyaluronate, and aloe vera which may help reduce occurrence and severity of radiation dermatitis. Both are commonly recommended and used by breast cancer patients undergoing external beam radiation therapy (EBRT). However, it is not known whether one is better than the other in treating or preventing radiation dermatitis.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.