Congenital Heart Disease Studies · Journal article
Current Cardiology Reports · August 28, 2026
A consensus or society position rather than new primary data.
This is a narrative review of transcatheter interventions and sex-specific considerations in women with congenital heart disease, highlighting underrepresentation of women in cardiovascular research and CHD trials. The review identifies gaps in evidence and proposes future research priorities, including use of artificial intelligence and machine learning for risk stratification, but presents no new empirical findings or quantified outcomes.
Journal article. Women with congenital heart disease undergoing or considered for transcatheter interventions..
Women with congenital heart disease are historically underrepresented in research studies and clinical trials, limiting generalizability of available evidence. Women with CHD are described as a vulnerable population given the relatively low prevalence of CHD. Emerging technologies and improved inclusion efforts offer an opportunity to better represent women in procedural outcome studies.
No specific data on comparative efficacy or safety of individual interventions in women versus men.
This review serves clinicians managing women with CHD by synthesizing current management approaches and highlighting sex-specific considerations and evidence gaps. It underscores the need for improved representation of women in CHD intervention trials and emerging technology applications.
A narrative review synthesizing current evidence on transcatheter interventions and sex-specific management considerations in women with congenital heart disease, without new empirical data or a systematic evidence synthesis.
This review serves clinicians managing women with CHD by synthesizing current management approaches and highlighting sex-specific considerations and evidence gaps. It underscores the need for improved representation of women in CHD intervention trials and emerging technology applications.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no reported figures. That is a gap in the analysis, not a judgement about the study.
PURPOSE OF REVIEW: To provide a review of current transcatheter interventions in women with congenital heart disease, with a focus on sex-specific considerations in diagnosis, management, and follow-up. RECENT FINDINGS: As the field of pediatric cardiology advances and patients with previously life-limiting diagnoses now survive well into adulthood, there is a growing need to pursue management strategies that improve quality of life. Unfortunately, in the treatment of cardiovascular disease, women have historically been underrepresented in research studies and clinical trials, which may limit the generalizability of available evidence and contribute to disparities in outcomes. Women with congenital heart disease (CHD) are an even more vulnerable population given the relatively low prevalence of CHD. This review discusses several CHD lesions and current trends in diagnosis, management, and follow-up in women. Additionally, it highlights sex-specific considerations in this unique patient population. Future initiatives and applications that may help improve the lifetime care of women with CHD are also reviewed. Although there have been increasing efforts to improve the inclusion of women in medical research in recent years, substantial gaps in representation remain. As emerging technologies are increasingly introduced in the CHD field, there is an important opportunity to improve the representation of women in studies evaluating procedural outcomes. Tools such as artificial intelligence and machine learning may help facilitate scalable screening and risk-stratification strategies for women with CHD.
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