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Life sciences · Journal article
International Journal of Medical Science and Clinical Research Studies · August 15, 2026
Early or partial results. Treat as a signal, not a conclusion.
This cross-sectional survey documents MDRO carriage in 21.45% of nasal and rectal samples from patients and healthcare workers in two haemodialysis units in Cameroon between November 2023 and April 2024. The prevalence is elevated in patients (91.2% of MDRO isolates) compared to staff (8.48%), but the small sample, lack of temporal design, and absence of clinical outcome data limit inference about transmission risk or intervention effectiveness.
Cross-sectional survey. 130 patients receiving haemodialysis and 25 healthcare workers in two referral hospitals in Yaounde, Cameroon. Patients had documented comorbidities including cardiovascular diseases and infections.. Intervention: Nasal and rectal swabs for MDRO screening. n = 155. Two referral hospitals in Yaounde, Cameroon.
MDRO isolated from 59 of 275 samples (21.45%): 54 from patients (91.2% of MDRO) and 5 from staff (8.48% of MDRO) MRSA, VRE, 3CPE, and ESBL-E were more common in patients than staff with no significant difference between the two hospitals No significant age-group difference in MDRO carriage (P=0.438)
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This surveillance snapshot suggests MDRO screening at haemodialysis unit admission and infection control review are warranted in this setting. However, the lack of follow-up, transmission data, or clinical outcomes means the findings do not yet guide specific interventions or predict patient risk.
A small cross-sectional survey of MDRO carriage in two hospitals without a control group, surveillance comparator, or temporal design; documents prevalence but cannot establish causation, trend, or clinical impact.
As stated by the source record.
Quoted from the source exactly as published.
This surveillance snapshot suggests MDRO screening at haemodialysis unit admission and infection control review are warranted in this setting. However, the lack of follow-up, transmission data, or clinical outcomes means the findings do not yet guide specific interventions or predict patient risk.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Background: The emergence and spread of Multidrug-resistant organisms (MDRO) represent a major public health issue, particularly amongst patients in haemodialysis units. Haemodialysis units regularly receive patients with renal failure, yet almost all hospitals in Cameroon with haemodialysis units lack a resistance surveillance program. The lack of data on the epidemiology of MDRO in haemodialysis units led us to conduct this study, with the aim of determining the frequency of MDRO carriage among patients and healthcare workers in haemodialysis units in Cameroon. Methods: Nasal and rectal swabs were collected from patients and healthcare staff in two referral hospitals of Yaounde, between November 2023 and April 2024. Bacteria isolated on selective media were identified by biochemical tests and mass spectrometry. Antibiotic resistance profiles and resistance phenotypes were detected according to EUCAST/CASFM 2023 recommendations. Results: A total of 155 participants were selected, including 130 patients and 25 staff members. Several comorbidities were identified among the patients, including cardiovascular diseases and infections. From the 275 samples collected we isolated 59 (21.45%) MDRO with 54 (91.2%) from patients and 5 (8.48%) from healthcare personnel. Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), third-generation cephalosporinase-producing Enterobacteriaceae (3CPE) and extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) were more represented among patients compared to healthcare personnel with no significant difference in the two hospitals. There was no significant difference between the age groups (P=0.438). The resistance profile of MDRO was similar in the two hospitals. Conclusion: This study revealed a high prevalence of MDRO in the haemodialysis unit, highlighting the need for systematic screening of patients on arrival at the haemodialysis unit and for the strengthening of standard precautions.
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