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Life sciences · Journal article
Atención Familiar · September 30, 2026
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Objective: To identify pharmacological and non-pharmacological treatments in primary care for patients with mixed anxiety-depression disorder and chronic pain. Methods: A descriptive cross-sectional study was conducted among patients with an established diagnosis of mixed anxiety-depression disorder who were beneficiaries of the Mexican Institute of Social Security (IMSS), enrolled in a family medicine unit (FMU), of either sex, and aged 18 to 55 years. The sample size was calculated using the formula for an infinite population, with an expected prevalence of 20%, resulting in n= 130. Medical records were reviewed using stratified random sampling from the database of the Medical Information and Clinical Records Department (ARIMAC) of the Family Medicine Unit. Patients with chronic pain were identified and administered the Pain Catastrophizing Scale. The data are presented as relative frequencies. Results: Of the total medical records reviewed (n= 130), 80% were women; the most common age group was 41 to 50 years; 36.9% were married; and 32.2% were engaged in office work. Regarding non-pharmacological management, 51% were referred to psychiatric services. Regarding pharmacological management, 36.15% received dual therapy with benzodiazepines and selective serotonin reuptake inhibitors. 54.2% of patients with chronic pain were treated at step two of the World Health Organization (WHO) analgesic ladder; nonsteroidal anti-inflammatory drugs were prescribed in 84.7% of cases. Conclusions: Pharmacological and nonpharmacological treatment of mixed anxiety-depression disorder and chronic pain in primary care was based primarily on dual therapy with benzodiazepines and selective serotonin reuptake inhibitors, referral to psychiatry, and the prescription of nonsteroidal anti-inflammatory drugs in accordance with the WHO analgesic ladder.