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Life sciences · Phase 1/2 Trial
ClinicalTrials.gov · September 18, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Phase 1/2 Trial.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
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This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
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Registry record from ClinicalTrials.gov (NCT07221344). This is a study registration, not published results. Lead sponsor: Arrowhead Pharmaceuticals. Recruitment status: RECRUITING. Phase: PHASE1, PHASE2. Study type: INTERVENTIONAL. Enrollment: 112 participants (ESTIMATED). Conditions: Alzheimer Disease, Alzheimer Disease, Early Onset. Interventions: DRUG: ARO-MAPT-SC; DRUG: Placebo. Primary outcome measures: Number of Participants with Treatment-Emergent Adverse Events (TEAEs) Over Time , Through End of Study (EOS; Day 315). Brief summary: Study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics of ARO-MAPT-SC compared to placebo in adult healthy volunteers and in participants with early Alzheimer's disease (AD), defined as mild cognitive impairment due to AD and mild AD dementia.