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Life sciences · Observational Study
ClinicalTrials.gov · October 15, 2026
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Observational Study.
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Registry record from ClinicalTrials.gov (NCT05868616). This is a study registration, not published results. Lead sponsor: Oslo University Hospital. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 80 participants (ESTIMATED). Conditions: Heart Failure, Pacemaker DDD, Cardiomyopathies, Heart Diseases, Cardiovascular Diseases. Interventions: DEVICE: Cardiac Resynchronization Therapy (CRT). Primary outcome measures: Reverse remodelling at 6 months follow-up , 6 months. Brief summary: Left bundle branch block (LBBB) exists in about 25% of patients with congestive heart failure and is associated with worsened prognosis. Cardiac resynchronization therapy (CRT) has been one of the most important advancements in the past two decades for patients with LBBB heart failure. However, 30-40% of patients receiving a CRT do not benefit from it. In this study, the investigators will test a noninvasive device to evaluate acute effect of CRT during implantation and at follow-up CRT controls. In addition, echocardiography will be performed during CRT turned ON and OFF to visualize the changes in intraventricular flow and functional parameters of the heart.