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Life sciences · Journal article
International Journal of Drug Delivery Technology · October 14, 2026
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BACKGROUND AND AIM: Among women worldwide, cervical cancer is the 4th most common cancer to be diagnosed and it ranks as the 4th most common cause of cancer related mortality.India accounts for 25% of the world's mortality rate as well.Patients with co morbid depression or anxiety experience more severe symptoms, take longer to recover, use more health care resources and have poorer prognosis and quality of life than those with single disorder.Therefore, evaluation of cancer patients should also include personal & family history of mental illness or suicide, current mental & physical status, side effects of treatment and disease, other stressors in the patient's life and necessary support available to patient.Hence the aim of this study is to assess the prevalence of depression and anxiety in cervical cancer patients and study its association with quality of life.METHODS: This cross-sectional observational study was conducted at R. L. Jalappa Hospital.All in-patients diagnosed with cervical cancer with age of 30 to 80 were included excluding the patients who were terminally ill or having neurological deficits or associated with previous psychiatry disorders.Informed consent was taken, demographic and clinical data was collected as per the proforma and relevant scales that are HAM-A, HDRS and EORTC QLQ-C30 were applied after obtaining informed consent for same. RESULTS:Of the 76 patients studied following findings were revealed-The mean age of the participants in this study was 53.8 years with majority being illiterate (71%), daily wage workers (54%), belonging to BPL category (96%) living in a nuclear setup (68%), bearing 1-3 children (62%), married between15-25 years (74%) and diagnosed within timeframe of 4-26 weeks (79%).Majority of patients were diagnosed with stage 3b cervical cancer (39%).Majority were noted to have moderate to severe anxiety (48.7%) and moderate depression (39.5%) with moderate QoL (67.1%).Stage 3b,3c,4a had severe depression compared to 2b(P<0.01).Patients without formal education had better quality of life when compared to literate ((P<0.01)).Employed participants have QoL compared to unemployed(P<0.01).Correlation of degree of anxiety and depression was statistically significant (P=< 0.01) likewise was correlation of quality of life and level of anxiety ((P<0.01)).The relationship of quality of life and level of depression also showed significance ((P<0.01)). CONCLUSION:According to this study anxiety and depression are prevalent in cervical carcinoma with moderate quality of life.This study throws light on the need for comprehensive approach to treatment of cervical cancer along with mental health.