Central Line Associated Bloodstream Infection (CLABSI) · Observational Study

Central Line-Associated Bloodstream Infection QI Project

ClinicalTrials.gov · August 5, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a planned observational study comparing an EHR-based alert intervention plus secure chat to usual care for reducing unnecessary central line days and CLABSI risk. No results have been posted in this registry record; the study has not yet begun recruitment.

What was studied

Observational. Central Line-associated Bloodstream Infection (CLABSI); age from 18 Years. Intervention: Usual Care; Secure Chat + Alert Cohort. Compared with: Usual care. n = 30. 1 site: United States.

Key findings

Safety

Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.

Who this may help

The source did not state who this applies to in practice.

Plain-language summary

This is a registry record for a planned observational study with no results posted; the intervention and comparator are described but outcomes are not yet reported.

Study design

As stated by the source record.

MethodsCohort model. Prospective time perspective. Primary outcome measure: Total number of central line days without a documented indication (assessed at Up to Month 3)

DesignObservational

PopulationCentral Line-associated Bloodstream Infection (CLABSI); age from 18 Years

Sample size30

InterventionUsual Care; Secure Chat + Alert Cohort

ComparatorUsual care

Setting1 site: United States

Reported figures

Quoted from the source exactly as published.

Planned enrollment30

Primary outcome measureTotal number of central line days without a documented indication, up to Month 3

Study typeObservational

Caveats

This is a registry record only; no results are reported and recruitment has not yet started.
Sample size of 30 is small and may lack power to detect clinically meaningful differences.
Observational design without randomization limits causal inference.
No information on study duration, site(s), inclusion/exclusion criteria, or analytical approach beyond primary outcome.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

limited

Observational design without randomization; compares alert intervention to usual care.

Directness

moderate

Directly addresses unnecessary CVC use and CLABSI risk in hospitalized adults.

Consistency

insufficient

No results reported; cannot assess consistency with other evidence.

Risk of bias

insufficient

Registry record does not report methodology details needed to assess bias.

Sample adequacy

limited

Estimated enrollment of only 30 participants is small for definitive conclusion.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT07746674). This is a study registration, not published results. Lead sponsor: NYU Langone Health. Recruitment status: NOT_YET_RECRUITING. Study type: OBSERVATIONAL. Enrollment: 30 participants (ESTIMATED). Conditions: Central Line-associated Bloodstream Infection (CLABSI). Primary outcome measures: Total number of central line days without a documented indication , Up to Month 3. Brief summary: This study evaluates a daily electronic health record (EHR) alert designed to reduce unnecessary central venous catheter (CVC) use among hospitalized adults. The alert identifies patients with an active CVC and no documented indication, prompting the first-contact provider to document line necessity. The study compares alert and a secure chat intervention to usual care, with the goal of reducing unnecessary line days and related CLABSI risk.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

NCT07746674Central Line Associated Bloodstream Infection (CLABSI)NYU Langone Health