Loading
Ischemic Stroke · Observational Study
ClinicalTrials.gov · September 4, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a planned observational cohort study registered to investigate whether blood-brain barrier disruption at stroke onset predicts cognitive decline over 3 years. No results are reported in this registry record, and the study remains in recruitment phase.
Observational. Ischemic Stroke; age from 18 Years. Intervention: Blood-brain barrier disruption assessment at stroke onset. n = 150. 1 site: United States.
This is a planned observational cohort study registered to investigate whether blood-brain barrier disruption at stroke onset predicts cognitive decline over 3 years. No results are reported in this registry record, and the study remains in recruitment phase.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
No clinical guidance can be drawn from this registry record. Results, if published, may help stratify post-stroke cognitive risk based on early BBB imaging.
This is an ongoing observational registry study with no results reported; it aims to establish an association between blood-brain barrier disruption and post-stroke cognitive decline over 3 years.
As stated by the source record.
Quoted from the source exactly as published.
No clinical guidance can be drawn from this registry record. Results, if published, may help stratify post-stroke cognitive risk based on early BBB imaging.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT05556395). This is a study registration, not published results. Lead sponsor: Johns Hopkins University. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 150 participants (ESTIMATED). Conditions: Ischemic Stroke. Primary outcome measures: Change in Cognition (Cognitive Decline) , Assessments occur every 6 months for 3 years. Brief summary: The goal of this study is to gain a better understanding of why some individuals who have suffered a stroke experience post-stroke cognitive decline. Specifically this study is testing whether global disruption of the blood-brain barrier detected at the time of the stroke is informative about the risk of post-stroke cognitive decline over the next 3 years.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.