Life sciences · Observational Study
ClinicalTrials.gov · November 3, 2026
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Observational Study.
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Registry record from ClinicalTrials.gov (NCT00900419). This is a study registration, not published results. Lead sponsor: University of Colorado, Denver. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 700 participants (ESTIMATED). Conditions: Esophageal Cancer, Head and Neck Cancer, Lung Cancer, Precancerous Condition. Interventions: OTHER: immunohistochemistry staining method; OTHER: laboratory biomarker analysis; OTHER: sputum cytology; PROCEDURE: biopsy. Primary outcome measures: Genetic mutations or altered growth factor expression , After study has completed. Brief summary: RATIONALE: Studying samples of sputum and tissue in the laboratory from patients with dysplasia or cancer may help doctors identify and learn more about biomarkers related to cancer. It may also help the study of cancer in the future. PURPOSE: This laboratory study is looking at biomarkers in patients with respiratory tract dysplasia or lung cancer, head and neck cancer, or aerodigestive tract cancer.