Heart Failure, Left Sided · Observational Study

Cardio-vascular Energy Transfer and Ventriculo-arterial Coupling in Heart Failure

ClinicalTrials.gov · September 11, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a completed observational pilot study investigating ventriculo-arterial energy transfer in heart failure patients during acute decompensation. No results are posted in this registry record, so the study's findings, effect sizes, and clinical relevance cannot be assessed from this source alone.

What was studied

Observational. Heart Failure, Left-sided. Intervention: Investigation of ventriculo-arterial energy transfer (no therapeutic intervention implied). n = 30. 1 site: Norway.

Key findings

Safety

Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.

Who this may help

Until published results are available, this registry record alone cannot guide clinical decision-making. The study's mechanistic focus on energy transfer may inform pathophysiology but requires linking to clinical outcomes and replication.

Plain-language summary

A completed single-centre observational pilot study with no published results reported; designed to investigate mechanistic endpoints (energy transfer) in a small sample without a comparator group.

Study design

As stated by the source record.

MethodsEcologic Or Community model. Prospective time perspective. Primary outcome measure: Cardio vascular energy transfer in heart failure patients. (assessed at During first 1-3 days after admission to hospital because of decompensated hear…)

DesignObservational

PopulationHeart Failure, Left-sided

Sample size30

InterventionInvestigation of ventriculo-arterial energy transfer (no therapeutic intervention implied)

Setting1 site: Norway

Reported figures

Quoted from the source exactly as published.

Sample size30

Primary outcome measureCardio-vascular energy transfer in heart failure patients during first 1-3 days after admission

Study typeObservational

Recruitment statusCOMPLETED

Clinical bottom line

Caveats

No results posted in this registry record; study outcomes, effect sizes, and statistical significance are not reported
Single-arm observational design without control group; cannot isolate causal effects
Pilot study with small sample (n=30); findings require confirmation in larger trials
Mechanistic endpoint (energy transfer) reported as primary outcome; clinical relevance and link to patient outcomes not established

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

limited

Observational, single-arm, no control group or comparator

Directness

moderate

Mechanistic endpoint (energy transfer) rather than clinical outcome

Consistency

insufficient

Registry record only; no results posted; cannot assess consistency

Risk of bias

insufficient

No methods or results reported; observational design without blinding stated

Sample adequacy

limited

30 participants enrolled; pilot study explicitly described as such

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT06200246). This is a study registration, not published results. Lead sponsor: St. Olavs Hospital. Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 30 participants (ACTUAL). Conditions: Heart Failure, Left-sided. Primary outcome measures: Cardio vascular energy transfer in heart failure patients. , During first 1-3 days after admission to hospital because of decompensated heart failure.. Brief summary: The goal of this pilot study is to investigate energy transfer fram the ventricle to the arteries in patients with heart failure, primary by investigating the total power.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

Heart Failure, Left SidedNCT06200246St. Olavs Hospital