Life sciences · Phase 4 Trial
ClinicalTrials.gov · September 21, 2026
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Phase 4 Trial.
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Registry record from ClinicalTrials.gov (NCT07186062). This is a study registration, not published results. Lead sponsor: Ain Shams University. Recruitment status: COMPLETED. Phase: PHASE4. Study type: INTERVENTIONAL. Enrollment: 60 participants (ACTUAL). Conditions: Acute Decompensated Heart Failure (ADHF), Cardiorenal Syndrome (CRS). Interventions: DRUG: Levosimendan; DRUG: Dobutamine; DRUG: Milrinone. Primary outcome measures: renal function parameters. , 7 days; renal function , 7 days; renal function , 7 days; renal function , 7 days; cardiac function , 7 days; cardiac function , 7 days; cardiac function , 7 days; cardiac function , 7 days. Brief summary: This study aimed to assess and compare the cardiac, renal, and clinical efficacy of Levosimendan (LEV), Dobutamine (DOB), and milrinone (MIL) in cases with acute decompensated heart failure (ADHF) complicated by renal impairment, with a focus on their role in the management of cardiorenal syndrome (CRS).