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Life sciences · Journal article
Medical Journal of Armed Police Force Nepal · August 1, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a small, single-centre descriptive survey documenting the prevalence of psychiatric and medical comorbidities in 60 admitted schizophrenia patients in Nepal. The study reports high rates of comorbidity (91.68% psychiatric, 61.68% medical) but provides no control group, no effect size comparisons, and no analytical testing. The findings serve primarily to document local clinical burden and hypothesis generation rather than to confirm or change practice.
Descriptive cross-sectional study. Admitted inpatients aged 18 years and above with a diagnosis of schizophrenia at a Department of Psychiatry in a medical college in Nepal.. n = 60. Department of Psychiatry of a medical college in Nepal.
55 of 60 patients (91.68%) had at least one comorbid psychiatric condition 37 of 60 patients (61.68%) had at least one comorbid medical condition Substance use disorder found in 37 patients (61.68%); anxiety in 35 (58.33%); depression in 30 (50%)
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The findings contribute to awareness of the high burden of comorbidity in schizophrenia and underscore the need for systematic screening. However, the small single-centre design and lack of a control group limit generalizability and do not establish prevalence rates that should immediately alter clinical practice guidelines.
Single-centre, small descriptive cross-sectional study of comorbidity prevalence in schizophrenia without a comparator group, control arm, or analytical hypothesis testing.
As stated by the source record.
Quoted from the source exactly as published.
The findings contribute to awareness of the high burden of comorbidity in schizophrenia and underscore the need for systematic screening. However, the small single-centre design and lack of a control group limit generalizability and do not establish prevalence rates that should immediately alter clinical practice guidelines.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Introduction: Patients with schizophrenia vary substantially relative to their symptoms, response to treatment, disease impact on function and biological correlates. Approximately 50% of patients with schizophrenia have at least one comorbid psychiatric or medical condition. This study was conducted to assess various psychiatric and medical comorbidities complicating the clinical picture of schizophrenia. Methods: A hospital-based descriptive cross-sectional study was conducted at the Department of Psychiatry of a medical college in Nepal from November 2018 to December 2019. All the admitted patients in Psychiatry Ward, 18 years and above with diagnosis of Schizophrenia were included. Patients admitted in intensive units and outpatient patient visits were excluded. Ethical approval was taken from Institutional Review Committee. A data collection tool which contained of semi-structured questionnaire was developed for data collection of clinical and demographic profile. The Positive and Negative Syndrome Scale, Beck Anxiety Inventory Nepali version, Beck Depression Inventory II Nepali version and CAGE Questionnaire for assessing syndrome of Schizophrenia, depression, anxiety and use of alcohol. The collected data was entered in the Microsoft Excel and Descriptive statistics were used to summarize and present the data. Results: Out of 60 patients, 55 (91.68%) and 37 (61.68%) had psychiatric and medical comorbidities respectively. Co-morbid psychiatric conditions such as substance use, anxiety and depression were found in 37 (61.68%), 35 (58.33%) and 30 (50%) of them. Sexual dysfunction and menstrual dysfunction were common co-morbidities followed by dyslipidaemia and electrolyte imbalance. Conclusions: This study found the substantial burden of comorbid conditions in the patients with schizophrenia.
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