Life sciences · Journal article
Journal of Cardiothoracic Surgery · August 19, 2026
Encouraging direction, but not yet definitive.
This single-center RCT of 182 post-AMI patients demonstrated that a 3-month multi-module interactive continuous care model significantly improved cardiac function indices (HR, LVFP, LVEF, SV), self-care ability (SCHFI), and quality of life measures (HPLP-II, MLHFQ) compared to routine care. The findings are limited to surrogate endpoints, short-term follow-up, and a single center; the authors acknowledge the need for larger multicenter studies before clinical translation.
Single-center, randomized controlled trial. Acute myocardial infarction patients after percutaneous coronary intervention.. Intervention: Multi-module interactive continuous care model delivered over 3 months (details of modules not specified in abstract).. Compared with: Routine cardiology care.. n = 182. Single center (location not specified in abstract)..
At 1 month, experimental group showed significantly lower HR and LVFP, higher LVEF and SV, and higher SCHFI and HPLP-II scores compared to control (all P < 0.05) At 3 months, all differences between experimental and control groups remained statistically significant (P < 0.05) MLHFQ scores were significantly lower in experimental group at both 1 and 3 months (all P < 0.05)
Only surrogate endpoints reported; no hard clinical outcomes (mortality, recurrent MI, heart failure hospitalization) provided.
If confirmed in larger multicenter trials, this model could inform post-AMI rehabilitation protocols by demonstrating benefit of structured interactive continuous care. Clinicians should recognize this as early evidence requiring validation before implementation in routine practice.
A single-center RCT with short-term surrogate endpoints (cardiac function, self-care, quality of life) showing statistically significant differences at 3 months, but limited by absence of hard clinical outcomes, modest sample size, and acknowledged need for multicenter confirmation.
As stated by the source record.
Quoted from the source exactly as published.
If confirmed in larger multicenter trials, this model could inform post-AMI rehabilitation protocols by demonstrating benefit of structured interactive continuous care. Clinicians should recognize this as early evidence requiring validation before implementation in routine practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Abstract Background Patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI) often experience impaired cardiac functional recovery, poor self-management capacity, and reduced quality of life. The multi-module interactive continuous care model, delivered through a structured and interactive approach, may help improve rehabilitation outcomes. This study evaluated the clinical efficacy of this care model in patients with AMI after PCI to provide evidence for optimizing post-AMI rehabilitation strategies. Methods In this randomized controlled trial, 182 AMI patients were enrolled between March and July 2025 and randomly assigned to a control group or an experimental group. The control group received routine cardiology care, while the experimental group received additional multi-module interactive continuous care for 3 months. Cardiac function indicators, including heart rate (HR), estimated left ventricular filling pressure (LVFP), left ventricular ejection fraction (LVEF), and stroke volume (SV), were assessed. Self-care ability was evaluated using the Self-Care of Heart Failure Index (SCHFI), and quality of life was measured by the Health-Promoting Lifestyle Profile-II (HPLP-II) and the Minnesota Living with Heart Failure Questionnaire (MLHFQ). Assessments were performed at baseline, 1 month, and 3 months after the intervention. Results At 1 month, the experimental group showed significantly lower HR and LVFP, and higher LVEF and SV compared to the control group (all P < 0.05). SCHFI and HPLP-II scores were also significantly higher, while MLHFQ scores were lower (all P < 0.05). These differences remained statistically significant at the 3-month follow-up, with intergroup differences remaining statistically significant ( P < 0.05). Conclusion The multi-module interactive continuous care model was associated with improved short-term cardiac function, self-care capacity, and quality of life in post-AMI patients after percutaneous coronary intervention. Given the single-center design and 3-month follow-up, these findings should be interpreted cautiously and confirmed in larger multicenter studies. Trial registration This trial was registered on Chinese Clinical Trial Registry ( https://www.chictr.org.cn/; ChiCTR2500098897).
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