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Life sciences · Interventional Study
ClinicalTrials.gov · September 30, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07849439). This is a study registration, not published results. Lead sponsor: St. Louis University. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 12 participants (ESTIMATED). Conditions: Overweight , Obesity. Interventions: BEHAVIORAL: Stair-Climbing Exercise Snacks. Primary outcome measures: Change in 2-Hour Postprandial Glucose Area Under the Curve (AUC) , Baseline (Day 1) and post-intervention (Day 15); Change in CGM-Derived Glucose Standard Deviation , Early intervention (Days 2-4) and late intervention (Days 11-13); Change in Aerobic Capacity (VO₂max or Estimated VO₂max) , Baseline (Day 0) and post-intervention (Day 15); Change in CGM-Derived Glucose Coefficient of Variation , Early intervention (Days 2-4) and late intervention (Days 11-13). Brief summary: This pilot study will evaluate whether brief bouts of stair climbing performed throughout the day for two weeks can improve metabolic health, cardiovascular fitness, and other health-related outcomes in adults with overweight or obesity who do not regularly exercise. Participants will complete approximately 6-8 brief stair-climbing "exercise snacks" per day for 14 days, with each bout consisting of approximately 60 total stair steps performed at a challenging but safe self-selected pace. Participants will complete baseline and post-intervention assessments at Saint Louis University. These assessments will include continuous glucose monitoring and standardized meal testing to evaluate glucose responses, as well as measures of aerobic fitness, anaerobic power, body composition, waist circumference, and muscular strength. The study will also evaluate adherence, perceived exercise intensity, and the feasibility of incorporating brief stair-climbing bouts into daily life.