Alzheimer S Disease / Control condition / Motor mental imagery · Interventional Study
ClinicalTrials.gov · July 31, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a planned interventional study comparing control, motor mental imagery, and action execution behavioral interventions for memory impairment in Alzheimer's disease patients. No results are available; the study is currently recruiting. Evidence quality cannot be assessed until the trial is completed and outcomes are reported.
Interventional, Non Randomized, Crossover, Open label, Other purpose. Alzheimer s Disease, Healhty; age from 60 Years; accepts healthy volunteers. Intervention: Control condition; Motor imagery intervention; Real action. Compared with: BEHAVIORAL: Control condition. n = 80. 3 sites: France.
This is a planned interventional study comparing control, motor mental imagery, and action execution behavioral interventions for memory impairment in Alzheimer's disease patients. No results are available; the study is currently recruiting. Evidence quality cannot be assessed until the trial is completed and outcomes are reported.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
This is an active registry record describing a planned interventional study with no results posted; evidence quality cannot be assessed until completion and outcome reporting.
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Registry record from ClinicalTrials.gov (NCT07632755). This is a study registration, not published results. Lead sponsor: Centre Hospitalier Universitaire de Saint Etienne. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 80 participants (ESTIMATED). Conditions: Alzheimer s Disease, Healhty. Interventions: BEHAVIORAL: Control condition; BEHAVIORAL: Motor mental imagery; BEHAVIORAL: Action execution. Primary outcome measures: Free recall score , at 1 week. Brief summary: In France, over 1.5 million people suffer from mild cognitive impairment, often a precursor to Alzheimer's disease (AD), whose global prevalence could reach 153 million by 2050. With no curative treatment available, maintaining patients' autonomy at home is essential to mitigate the negative effects of institutionalization and reduce economic costs. Non-pharmacological approaches, such as cognitive training, have shown potential in stabilizing cognitive functions. Research suggests that motor networks and procedural memory remain relatively preserved in early AD, and bodily engagement during encoding enhances memory. For patients with motor impairments, motor imagery (MI) activates these networks without actual movement. Additionally, dynamic visual cues, like videos, reduce cognitive load compared to static images. This project aims to combine real action, MI, and dynamic visual supports to optimize memory. By validating 120 videos of daily activities, it will assess the impact of action on recall, evaluate MI's effectiveness for patients with mobility limitations, and confirm the superiority of videos over static images. The results could support the development of digital tools, such as serious games, to enhance patients' autonomy and address aging-related challenges.
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