Healthy Minds Program / Healthy Minds Brian Games / Care as usual · Interventional Study

The Lucida Project

ClinicalTrials.gov · August 14, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

The Lucida Project is a registered interventional trial planned to enroll 1500 participants with depression to evaluate whether the Healthy Minds Program reduces depression symptoms measured by PHQ-9 over 4 weeks. No results are yet available; this is a protocol registration only.

What was studied

Interventional, Randomized, Parallel, Open label, Treatment purpose. Depression Disorder; age from 18 Years; to 84 Years; accepts healthy volunteers. Intervention: Healthy Minds Program (HMP). Compared with: Active control group — Active Comparator; Usual care group — Active Comparator. n = 1,500. University of Wisconsin, Madison (lead sponsor); other sites not specified..

Key findings

Safety

Effect sizes, safety data, and statistical significance cannot be assessed from registry record alone.

Who this may help

The source did not state who this applies to in practice.

Plain-language summary

This is a registered but not-yet-recruiting interventional study with no results posted; it describes planned enrollment and primary outcome measures only.

Study design

As stated by the source record.

MethodsPrimary outcome measure: Change in Physical Health Questionnaire depression scale (PHQ-9) (assessed at Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks, 3 months)

DesignInterventional, Randomized, Parallel, Open label, Treatment purpose

PopulationDepression Disorder; age from 18 Years; to 84 Years; accepts healthy volunteers

Sample size1,500

InterventionHealthy Minds Program (HMP)

ComparatorActive control group — Active Comparator; Usual care group — Active Comparator

SettingUniversity of Wisconsin, Madison (lead sponsor); other sites not specified.

Reported figures

Quoted from the source exactly as published.

Planned sample size1500

Primary outcome measureChange in Physical Health Questionnaire depression scale (PHQ-9)

Assessment timepointsBaseline, 1 week, 2 weeks, 3 weeks, 4 weeks, 3 months

Study duration4-week well-being program

Caveats

Study not yet recruiting; no results reported.
Randomization scheme, blinding, and allocation method not disclosed.
Comparator assignment (device vs. behavioral vs. care as usual) not clarified.
Effect sizes, safety data, and statistical significance cannot be assessed from registry record alone.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

insufficient

Interventional study registered; randomization, blinding, and control allocation not specified.

Directness

moderate

Primary outcome is PHQ-9 depression scale, a validated patient-reported measure of depression severity.

Consistency

insufficient

No results reported; consistency cannot be assessed.

Risk of bias

insufficient

Study not yet recruiting; blinding, allocation concealment, and conduct details unknown.

Sample adequacy

moderate

Estimated 1500 participants; adequacy depends on effect size and study design not yet disclosed.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT07678242). This is a study registration, not published results. Lead sponsor: University of Wisconsin, Madison. Recruitment status: NOT_YET_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 1500 participants (ESTIMATED). Conditions: Depression Disorder. Interventions: DEVICE: Healthy Minds Program; BEHAVIORAL: Healthy Minds Brian Games; BEHAVIORAL: Care as usual. Primary outcome measures: Change in Physical Health Questionnaire depression scale (PHQ-9) , Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks, 3 months. Brief summary: The purpose of this clinical trial is to learn about the impact of the Healthy Minds Program (HMP) on measurements of well-being. The main question it aims to answer is: * Does use of HMP reduce symptoms of depression? Participants will complete a 4-week well-being program.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

University of Wisconsin, MadisonNCT07678242Healthy Minds ProgramHealthy Minds Brian GamesCare as usualDepression Disorder