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Efferon CT / Acute Pancreatitis Without Necrosis Or Infection · Interventional Study
ClinicalTrials.gov · September 11, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a completed interventional study registration for a device (Efferon CT) combined with high-volume hemofiltration in acute pancreatitis without necrosis or infection. No results are posted in this registry record; only the study protocol and planned primary outcome (organ dysfunction indicators at 1–72 hours) are described.
Interventional, Randomized, Parallel, Open label, Treatment purpose. Acute Pancreatitis Without Necrosis or Infection; age from 18 Years; to 75 Years. Intervention: Basic therapy + Efferon CT + HVHF. Compared with: Baseline therapy — No Intervention. n = 28. 1 site: Russia.
This is a completed interventional study registration for a device (Efferon CT) combined with high-volume hemofiltration in acute pancreatitis without necrosis or infection. No results are posted in this registry record; only the study protocol and planned primary outcome (organ dysfunction indicators at 1–72 hours) are described.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
This is a completed registry record reporting planned enrollment and primary outcome measures only, with no results posted; the study design is interventional but results are not yet available for evidence assessment.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT05694988). This is a study registration, not published results. Lead sponsor: Efferon JSC. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 28 participants (ACTUAL). Conditions: Acute Pancreatitis Without Necrosis or Infection. Interventions: DEVICE: Efferon CT. Primary outcome measures: Effect of the combined use of the Efferon CT device and HVHF on indicators of organ dysfunction , 1-72 hours. Brief summary: Mortality from severe acute pancreatitis reaches 42%. The prognosis of acute pancreatitis is associated with the development of acute inflammatory response syndrome (SIRS) and multiple organ failure (MOF). Due to the lack of etiological therapy, the treatment of acute pancreatitis is predominantly symptomatic. Severity and mortality are associated with early systemic inflammatory response syndrome (SIRS) and septic complications in the later stages of the disease. In connection with a pronounced inflammatory reaction ("cytokine storm") in the early phase of endogenous intoxication of acute pancreatitis, a promising therapeutic approach is the extracorporeal removal of cytokines. This prospective study intends to study the effect of hemoperfusion (Efferon CT) in combination with high-volume hemofiltration (HVHF) on the severity of symptoms of endogenous intoxication and indicators of organ dysfunction in acute pancreatitis.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.