Life sciences · Phase 2/3 Trial
ClinicalTrials.gov · September 29, 2026
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Phase 2/3 Trial.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
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Registry record from ClinicalTrials.gov (NCT07846865). This is a study registration, not published results. Lead sponsor: Woolcock Institute of Medical Research. Recruitment status: NOT_YET_RECRUITING. Phase: PHASE2, PHASE3. Study type: INTERVENTIONAL. Enrollment: 256 participants (ESTIMATED). Conditions: Sleep Apnoea, Obesity & Overweight, Sleep Apnea Syndrome, Obstructive. Interventions: DEVICE: Continuous Positive Airway Pressure; DRUG: Tirzepatide. Primary outcome measures: Breathing Disturbance Index (BDI) , The mean BDI measured over 28 nights of monitoring is calculated for baseline (Weeks -4 to 0) and follow-up (Weeks 48 to 52). Brief summary: When used, continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea (OSA), a condition that is mainly caused by overweight and obesity. However, CPAP is plagued by poor adherence and high rates of discontinued use leaving most patients undertreated and at risk of serious health complications. This study aims to test whether new effective weight loss pharmacotherapy is superior to CPAP for alleviating OSA and improving health outcomes.