Life sciences · Observational Study
ClinicalTrials.gov · September 23, 2026
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Observational Study.
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Registry record from ClinicalTrials.gov (NCT05327881). This is a study registration, not published results. Lead sponsor: Assiut University. Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 60 participants (ACTUAL). Conditions: Septic Shock. Interventions: DIAGNOSTIC_TEST: Plasma renin concentrations will be measured at enrollment and at 24, 48, and 72 hours. Whole blood lactate measurements will be performed according to normal standard of care.. Primary outcome measures: The primary endpoint was 28-day mortality. , 28 days. Brief summary: Whole blood lactate concentration is widely used in shock states to assess perfusion. We aimed to determine if the change in plasma renin concentration over time would be superior to the change in lactate concentration for predicting 28-day mortality in septic shock patients.