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Standard treatment / Enalapril / Hypertensive Disorder of Pregnancy · Phase 3 Trial
ClinicalTrials.gov · August 6, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is an active Phase 3 trial registration evaluating the feasibility of randomizing postpartum women with hypertensive disorders of pregnancy to enalapril versus standard treatment. No clinical outcomes or efficacy data have been reported; the study is still recruiting and measures only enrollment and retention at 4 months.
Phase 3, Interventional, Randomized, Parallel, Single masking, Treatment purpose. Preeclampsia, Hypertensive Disorder of Pregnancy, Hypertension, Gestational Hypertension, Gestational Hypertension After Childbirth; Female; age from 18 Years. Intervention: Enalapril. Compared with: Standard treatment — Active Comparator. n = 60. 1 site: United States.
This is an active Phase 3 trial registration evaluating the feasibility of randomizing postpartum women with hypertensive disorders of pregnancy to enalapril versus standard treatment. No clinical outcomes or efficacy data have been reported; the study is still recruiting and measures only enrollment and retention at 4 months.
Primary outcomes are feasibility and retention, not cardiovascular efficacy or safety.
Clinicians should note this trial is in the recruitment phase and does not yet provide evidence regarding cardiovascular protection with enalapril postpartum. Results on feasibility and blood pressure effects are expected but not yet available in this registry record.
This is an active clinical trial registration with no reported results; the study is still recruiting and measures feasibility and retention rather than clinical efficacy.
As stated by the source record.
Quoted from the source exactly as published.
Clinicians should note this trial is in the recruitment phase and does not yet provide evidence regarding cardiovascular protection with enalapril postpartum. Results on feasibility and blood pressure effects are expected but not yet available in this registry record.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07222852). This is a study registration, not published results. Lead sponsor: Women and Infants Hospital of Rhode Island. Recruitment status: RECRUITING. Phase: PHASE3. Study type: INTERVENTIONAL. Enrollment: 60 participants (ESTIMATED). Conditions: Preeclampsia, Hypertensive Disorder of Pregnancy, Hypertension, Gestational Hypertension, Gestational Hypertension After Childbirth. Interventions: DRUG: Enalapril; OTHER: Standard treatment. Primary outcome measures: Feasibility of enrollment , 4 months; Feasibility of retention , 4 months. Brief summary: The purpose of this study is to learn if postpartum women are willing to be randomized to different blood pressure medicines after delivery and how that affects blood pressure in women with hypertensive disorders of pregnancy.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.