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Life sciences · Interventional Study
ClinicalTrials.gov · September 29, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT01560871). This is a study registration, not published results. Lead sponsor: Texas Woman's University. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 16 participants (ACTUAL). Conditions: Heart Failure NYHA Class II, Heart Failure NYHA Class III. Interventions: BEHAVIORAL: High-intensity IMT plus walking; BEHAVIORAL: Low-intensity IMT plus walking. Primary outcome measures: Change From Baseline in Mean Minnesota Living With Heart Failure Questionnaire Score , Baseline and 6 weeks; Change From Baseline in Mean Score of Physical Component of the SF-36 Questionnaire , Baseline and 6 weeks. Brief summary: Individuals with chronic heart failure need a "safe and effective" exercise program that could enhance their quality of life. In this study, we examined whether an experimental exercise program of autonomous walking and high-intensity Inspiratory Muscle Training (IMT) could result in better effects on respiratory muscle strength (PImax), cardiovascular endurance, quality of life, and physical activity, when compared to autonomous walking and "sham" IMT program, in adults with chronic heart failure.