Life sciences · Phase 1 Trial
ClinicalTrials.gov · November 2, 2026
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Phase 1 Trial.
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Registry record from ClinicalTrials.gov (NCT07911514). This is a study registration, not published results. Lead sponsor: AstraZeneca. Recruitment status: NOT_YET_RECRUITING. Phase: PHASE1. Study type: INTERVENTIONAL. Enrollment: 60 participants (ESTIMATED). Conditions: Healthy Participants. Interventions: DRUG: AZD9550 solution for injection; DRUG: AZD6234 solution for injection; DRUG: Formulation 1 solution for injection; DRUG: Formulation 2 solution for injection; DRUG: Formulation 3 solution for injection; DRUG: Formulation 4 solution for injection. Primary outcome measures: Maximum observed plasma concentration (Cmax) , Plasma sample collection from pre dose to Day 22; Area under the curve from time 0 to the time of last quantifiable concentration (AUClast) , Plasma sample collection from pre dose to Day 22; Area under the curve from time 0 extrapolated to infinity (AUCinf) , Plasma sample collection from pre dose to Day 22. Brief summary: This study in healthy volunteers aims to compare blood levels and side effects after administration of different formulations of two test medicines, AZD9550 and AZD6234. This study will take place at one site in Nottingham, United Kingdom, and will randomize 60 healthy men and women aged 18-55 years living with overweight/obesity.