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Pain Catastrophizing Scale / Pain-Pressure Threshold / Central Sensitisation · Observational Study
ClinicalTrials.gov · August 14, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a prospective observational registry record for a planned two-phase study investigating preoperative and perioperative factors associated with chronic pain after hysterectomy. No results have been reported; the study is still recruiting and outcome data collection is ongoing. The record documents the intended assessments but provides no evidence of efficacy or association.
Observational. Hysterectomy, Chronic Pain, Central Sensitisation, Anxiety Depression; Female; age from 21 Years; to 80 Years; accepts healthy volunteers. Intervention: Control group for CPHP; Chronic Post-Hysterectomy Pain (CPHP); Control group for significant postoperative pain; Significant postoperative pain. n = 436. 1 site: Singapore.
This is a prospective observational registry record for a planned two-phase study investigating preoperative and perioperative factors associated with chronic pain after hysterectomy. No results have been reported; the study is still recruiting and outcome data collection is ongoing. The record documents the intended assessments but provides no evidence of efficacy or association.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
This is an observational registry record describing a planned study with no results posted; enrollment is ongoing and primary outcomes have not yet been reported.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT04014829). This is a study registration, not published results. Lead sponsor: KK Women's and Children's Hospital. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 436 participants (ESTIMATED). Conditions: Hysterectomy, Chronic Pain, Central Sensitisation, Anxiety Depression. Interventions: DIAGNOSTIC_TEST: Pain-Pressure Threshold; DIAGNOSTIC_TEST: Mechanical Temporal Summation; DIAGNOSTIC_TEST: Hospital Anxiety and Depression Scale; DIAGNOSTIC_TEST: Pain Catastrophizing Scale; DIAGNOSTIC_TEST: Central Sensitization Inventory; DIAGNOSTIC_TEST: Fear-Avoidance Component Score; DIAGNOSTIC_TEST: EQ-5D; DIAGNOSTIC_TEST: heart rate variability; DIAGNOSTIC_TEST: Anxiety, anticipated pain, anticipated analgesia; DIAGNOSTIC_TEST: State-trait anxiety inventory; DIAGNOSTIC_TEST: Beck's Depression Inventory. Primary outcome measures: Chronic Post-Hysterectomy Pain at 4 months , 4 months after hysterectomy; Significant postoperative pain at 24 hours , 24 hours after hysterectomy. Brief summary: Phase 1 (started in July 2019): Central Sensitization Inventory (CSI), Fear-Avoidance Components Scale (FACS), pain-pressure threshold are factors associated with chronic post-hysterectomy pain (CPHP), but a complete understanding on the development of CPHP is lacking. The study aims to identify clinically-relevant factors for CPHP that can be reliably assessed preoperatively. === Phase 2 (anticipated start May 2022): In addition to above factors, the association between heart rate variability (HRV) parameters, anxiety level, anticipated pain, and anticipated analgesia requirement with significant postoperative pain and CPHP will be investigated.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.