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Desflurane / Obesity / Sevoflurane-Desflurane · Phase 4 Trial
ClinicalTrials.gov · August 5, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a planned Phase 4 randomized non-inferiority trial comparing anesthetic swap strategy (sevoflurane-to-desflurane) versus continuous desflurane in adults undergoing bariatric surgery, with extubation time as the primary outcome. The study has not yet recruited participants and no results are available.
Phase 4, Interventional, Randomized, Parallel, Double masking, Treatment purpose. Obesity, Bariatric Surgery; age from 18 Years. Intervention: Continuous Desflurane; Sevoflurane-Desflurane Swap. Compared with: Continuous desflurane anesthesia. n = 82. 1 site: Chile.
This is a planned Phase 4 randomized non-inferiority trial comparing anesthetic swap strategy (sevoflurane-to-desflurane) versus continuous desflurane in adults undergoing bariatric surgery, with extubation time as the primary outcome. The study has not yet recruited participants and no results are available.
Registry record only; no efficacy or safety results posted; study not yet recruiting.
If non-inferiority is demonstrated, the anesthetic swap strategy could reduce perioperative anesthetic costs without compromising recovery time. Results are not yet available and should be awaited before any clinical implementation is considered.
This is a clinical trial registry record with no reported results; the study is not yet recruiting. No efficacy or safety data are available to assess.
As stated by the source record.
Quoted from the source exactly as published.
If non-inferiority is demonstrated, the anesthetic swap strategy could reduce perioperative anesthetic costs without compromising recovery time. Results are not yet available and should be awaited before any clinical implementation is considered.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07748247). This is a study registration, not published results. Lead sponsor: Clínica Dávila. Recruitment status: NOT_YET_RECRUITING. Phase: PHASE4. Study type: INTERVENTIONAL. Enrollment: 82 participants (ESTIMATED). Conditions: Obesity, Bariatric Surgery. Interventions: DRUG: Desflurane; DRUG: Sevoflurane-Desflurane. Primary outcome measures: Extubation Time , Perioperative. Brief summary: This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to continuous desflurane anesthesia with respect to extubation time in adults undergoing elective laparoscopic bariatric surgery. Secondary outcomes include time to achieve a Patient State Index (PSi) greater than 80, time to achieve an Aldrete score of at least 8, incidence of postoperative nausea and vomiting, post-anesthesia care unit length of stay, and desflurane-related costs.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.