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Life sciences · Interventional Study
ClinicalTrials.gov · November 2, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07908628). This is a study registration, not published results. Lead sponsor: New Life Psychiatric Rehabilitation Association. Recruitment status: NOT_YET_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 78 participants (ESTIMATED). Conditions: Depression - Major Depressive Disorder, Generalised Anxiety Disorder, Anxiety Disorder (Panic Disorder or GAD), Depressive and Anxiety Disorders. Interventions: BEHAVIORAL: Internet-based Unified Protocol (iUP); OTHER: Waitlist Control Group. Primary outcome measures: Patient Health Questionnaire-9 (PHQ-9) , Intake, weekly during the 14-week intervention period (Weeks 1 - 14), and at 1-, 2-, 3-, 6-, and 12-month follow-ups after the end of the intervention.; Generalized Anxiety Disorder-7 (GAD-7) , Intake, weekly during the 14-week intervention period (Weeks 1 - 14), and at 1-, 2-, 3-, 6-, and 12-month follow-ups after the end of the intervention.. Brief summary: The goal of this clinical trial is to learn if an internet-based Unified Protocol (iUP) intervention is effective for treating depression and anxiety disorders in Hong Kong young adults aged 18-29 years. This study is conducted within the eClinic, a public mental health support service provided by a Hong Kong non-government organisation (NGO). The main questions it aims to answer are: * Is the iUP intervention effective in treating depression and anxiety disorders? * How long is the treatment effect sustained after the intervention ends? * Does the intervention also improve real-world functioning, such as occupational and academic performance? Researchers will compare participants who receive the iUP intervention immediately with those in a wait-list control group (who receive no intervention during the waiting period) to evaluate the effectiveness of iUP. Participants will: * Receive a 14-week iUP intervention either immediately or after a 14-week waiting period according to randomisation * Complete weekly and follow-up questionnaires throughout the study period