Life sciences · Interventional Study
ClinicalTrials.gov · October 13, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07346183). This is a study registration, not published results. Lead sponsor: University of Chicago. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 330 participants (ESTIMATED). Conditions: Alzheimer s Disease, Dementia, Caregiver, Loneliness, Health-Related Social Needs, Social Care, Healthcare Utilization, End of Life Care, Caregiver Burden, Anxiety, Stress, Depression, Self-Efficacy, Peer Support, Implementation Science, Advance Care Planning. Interventions: OTHER: CommunityRx-Dpeer. Primary outcome measures: Caregiver loneliness at 6 months , 6 months; Caregiver's self-efficacy for finding end of life/advance care planning resources for the person with dementia at 12 months , 12 months. Brief summary: The CRxDpeer intervention, delivered by a trained peer navigator, in practice called a "peer mentor", includes three evidence-based components: (a) focused education about common social (e.g., food and housing insecurity) and caregiving (e.g., respite and end of life care) needs, (b) activation of personalized community resource information for social and caregiving needs through delivery of a resource list (HealtheRx) at the baseline encounter and coaching on how to communicate with service providers, coordinate services and manage social support (e.g., connect with their peer navigator, reach out to friends or relatives for support, identify support groups, etc.) and (c) ongoing navigation-focused support meant to boost the baseline intervention, including a series of proactive text messages over 12 months. During this time, the subject can respond to and communicate with the peer navigator for ongoing support.