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EEG Brain Oscillations / Alzheimer's Disease (AD) and Related Disorders / Gamma auditory stimulation device (active setting) · Interventional Study
ClinicalTrials.gov · August 17, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a registry record for a planned randomized, double-blind, placebo-controlled trial of 40 Hz auditory stimulation in older adults with mild cognitive impairment or mild dementia. No results have been posted; the study is currently recruiting participants. Evidence of efficacy cannot be assessed until outcome data are available.
Interventional, Randomized, Parallel, Double masking, Treatment purpose. EEG Brain Oscillations, Alzheimer's Disease (AD) and Related Disorders, Cognitive Dysfunction; age from 60 Years. Intervention: 40Hz music group. Compared with: Non-40Hz music group — Sham Comparator. n = 70. 1 site: Taiwan.
This is a registry record for a planned randomized, double-blind, placebo-controlled trial of 40 Hz auditory stimulation in older adults with mild cognitive impairment or mild dementia. No results have been posted; the study is currently recruiting participants. Evidence of efficacy cannot be assessed until outcome data are available.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
No clinical impact can be assessed from this registry record, as results are not yet reported. Clinicians should await outcome publication before drawing conclusions about the efficacy of 40 Hz auditory stimulation for cognitive decline.
This is a clinical trial registry record describing a planned study with no results posted; enrollment is ongoing and outcome data are not yet available.
As stated by the source record.
Quoted from the source exactly as published.
No clinical impact can be assessed from this registry record, as results are not yet reported. Clinicians should await outcome publication before drawing conclusions about the efficacy of 40 Hz auditory stimulation for cognitive decline.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07087951). This is a study registration, not published results. Lead sponsor: Chang Gung Memorial Hospital. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 70 participants (ESTIMATED). Conditions: EEG Brain Oscillations, Alzheimer's Disease (AD) and Related Disorders, Cognitive Dysfunction. Interventions: DEVICE: Gamma auditory stimulation device (active setting); DEVICE: Gamma auditory stimulation device (sham setting). Primary outcome measures: Changes in neurophysiological function. , baseline (T1), through intervention completion, an average of 3 month (T2), three-month after intervention completion (T3). Brief summary: Animal studies have shown that 40 Hz auditory stimulation alone can improve spatial memory and reduce Aβ deposition. However, human studies using 40 Hz auditory stimulation alone remain limited. Therefore, this study will use a randomized, double-blind, placebo-controlled design to investigate the effects of 40 Hz auditory stimulation on cognitive function, EEG activity, sleep quality, and quality of life in older adults with mild cognitive impairment (MCI) or mild dementia.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.