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Life sciences · Interventional Study
ClinicalTrials.gov · September 23, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07835698). This is a study registration, not published results. Lead sponsor: National Health Research Institutes, Taiwan. Recruitment status: NOT_YET_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 100 participants (ESTIMATED). Conditions: Breast Cancer, Psychological Distress. Interventions: BEHAVIORAL: Internet-Based Cognitive Behavioral Therapy Program for Breast Cancer Survivors; OTHER: Treatment as Usual (TAU). Primary outcome measures: Change in Psychological Distress as Assessed by the Depression, Anxiety and Stress Scale-21 , Baseline to Week 9. Brief summary: Breast cancer and its treatment can cause ongoing emotional distress, including anxiety, depressive symptoms, stress-related reactions, and difficulties adjusting to life after treatment. This study evaluates an 8-week Internet-based cognitive behavioral therapy (ICBT) program designed to support psychological adjustment and improve quality of life among adults with stage I-III breast cancer who have completed primary cancer treatment. Approximately 100 participants will be randomly assigned to either an ICBT group or a control group. Participants in the ICBT group will receive treatment as usual together with the 8-week online program, while participants in the control group will receive treatment as usual alone during the main study period. The study will compare changes in anxiety, depressive symptoms, post-traumatic stress symptoms, and quality of life between the two groups.