Life sciences · Phase 1 Trial
ClinicalTrials.gov · October 27, 2026
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Phase 1 Trial.
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Registry record from ClinicalTrials.gov (NCT07213791). This is a study registration, not published results. Lead sponsor: Eli Lilly and Company. Recruitment status: RECRUITING. Phase: PHASE1. Study type: INTERVENTIONAL. Enrollment: 340 participants (ESTIMATED). Conditions: Ovarian Neoplasms, Breast Neoplasms, Pancreatic Intraductal Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms, Stomach Neoplasms, Cholangiocarcinoma, Advanced Solid Tumors. Interventions: DRUG: LY4337713. Primary outcome measures: Phase 1a: Percentage of Participants with Dose Limited Toxicity (DLT) Toxicities , Cycle 1 (28 days); Phase 1b: Objective Response Rate (ORR): Percentage of Participants with Best Response of Complete Response (CR) or Partial Response (PR) , Baseline through imaging follow-up, up to 5 years. Brief summary: This is a study of LY4337713 in participants with certain types of cancer that is advanced or has spread. Participants must have cancer with high levels of a protein called fibroblast activation protein (FAP). The purpose of this study is to evaluate safety, side effects, and efficacy of LY4337713. In addition, this study will evaluate how much LY4337713 gets into the bloodstream, how it is broken down, and how long it takes the body to get rid of it. For each participant, the study will last about 5 years.