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Life sciences · Interventional Study
ClinicalTrials.gov · September 21, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Interventional Study.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
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Registry record from ClinicalTrials.gov (NCT07831538). This is a study registration, not published results. Lead sponsor: Kaiser Permanente. Recruitment status: NOT_YET_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 13714 participants (ESTIMATED). Conditions: CHF - Congestive Heart Failure. Interventions: BEHAVIORAL: Digital Outreach. Primary outcome measures: Refill of at least one overdue GDMT medication (within 14 days) , Within 14 days after outreach. Brief summary: The goal of the ADHERE-HF study is to evaluate whether digital outreach improves medication refill, adherence, and clinical outcomes among adults with heart failure who are overdue for a refill of an eligible guideline-directed medical therapy (GDMT) medication. The main question it aims to answer is: Does digital outreach using interactive text messages or automated telephone calls increase short-term refill of overdue heart failure medications compared with usual care? The study team, working with operational partners, will evaluate the effectiveness of a digital outreach strategy delivered through existing health system communication channels. Participants who have opted in to pharmacy text messaging will receive interactive text messages, while those who have not opted in will receive an interactive automated telephone call. The comparison group will receive usual care with no additional study-specific outreach. Participants will: * Be assigned to digital outreach or usual care * Potentially receive an interactive text message or automated telephone call encouraging refill of overdue heart failure medications * Be monitored for medication refill within 14 and 28 days * Potentially receive additional outreach if another eligible heart failure medication becomes overdue during the 12-month follow-up period * Have their medication refill patterns, longer-term adherence, hospitalizations, and mortality tracked using routinely collected health system data