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Life sciences · Interventional Study
ClinicalTrials.gov · September 22, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT05631184). This is a study registration, not published results. Lead sponsor: The Hong Kong Polytechnic University. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 250 participants (ACTUAL). Conditions: Depressive Symptoms, Depressive Disorder, Depression. Interventions: BEHAVIORAL: Self-administered acupressure group; BEHAVIORAL: Mental health education group. Primary outcome measures: Patient Health Questionnaire (PHQ) , It will be measured at baseline; Patient Health Questionnaire (PHQ) , It will be measured at week 4 from baseline; Patient Health Questionnaire (PHQ) , It will be measured at week 8 from baseline; Patient Health Questionnaire (PHQ) , It will be measured at week 12 from baseline. Brief summary: The goal of this clinical trial is to examine the effects of self-administered acupressure intervention for alleviating depressive symptoms among people with depression. It is hypothesized that the self-administered acupressure group would have a great improvement in depressive symptoms as measured by the Patient Health Questionnaire compared with the mental health education group across the 12-week intervention period. The main questions it aims to answer are: * Is the self-administered acupressure intervention more effective for alleviating depression and other related outcomes compared to the mental health education group among depressed individuals? * Is the self-administered acupressure intervention acceptable and feasible for depressed individuals to alleviate depression? Participants will be randomized into self-administered acupressure group or mental health education group based on the group allocation with a 1:1 ratio. Participants will attend two weekly 120-min self-administered acupressure training or mental health education, respectively.