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Life sciences · Observational Study
ClinicalTrials.gov · October 29, 2026
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Observational Study.
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Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
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Registry record from ClinicalTrials.gov (NCT01352949). This is a study registration, not published results. Lead sponsor: National Institutes of Health Clinical Center (CC). Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 199 participants (ACTUAL). Conditions: Bone Diseases, Obesity, Healthy Volunteers. Primary outcome measures: Output variables provided by the Matlab stereophotogrammetry analysis program , after accrual of 50 subjects, 100 subjects, and all subjects; Other variables calculated from the Matlab stereophotogrammetry output variables , after accrual of 50 subjects, 100 subjects, and all subjects. Brief summary: Background: \- Stereophotogrammetry (SP) uses four sets of digital cameras to generate a three-dimensional computer image. Unlike other types of evaluations which require radiation, SP only uses computer images to learn more about physical deformities such as scoliosis or about the placement of fat on the body. To refine the SP process, researchers are interested in collecting images and body data from individuals with skeletal structural problems such as scoliosis or chest wall deformities, individuals who are overweight or obese, and healthy volunteers. Objectives: \- To use stereophotogrammetry to study different individual body types and refine existing imaging techniques. Eligibility: \- Individuals at least 2 years of age who have spine, rib, or chest wall deformities; are overweight or obese (body mass index greater than 25); or are healthy volunteers. Design: * Participants will be screened with a physical examination and medical history. The physical examination will include measurements of range of motion and joint mobility, torso width and length, and other observational data. * Healthy volunteers and participants in the obesity group will also have bioelectric spectroscopy (bioimpedance), which uses an additional machine to measure how fat is spread in different parts of the body. * After the physical examination has been completed, participants will have SP photographs taken. Participants will be asked to remove all clothing from the torso, stand with arms raised at the center of four cameras, and remain still while several images are taken. A complete image takes less than 1 second. * Participants with spine or rib deformities, or who are in the obesity group, may also volunteer to return for followup SP imaging, once a year for 5 years, to study progress over time....