Endoscopic Band Ligation / Obesity · Interventional Study

Endo-Band: Endoscopic Band Ligation for Weight Loss

ClinicalTrials.gov · September 10, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a registry record for a planned first-in-human feasibility study of endoscopic band ligation for weight loss. No results are reported. The study is recruiting an estimated 5 participants to assess weight loss at 3 months.

What was studied

Interventional, Single Group, Open label, Treatment purpose. Obesity; age from 18 Years; to 65 Years. Intervention: Band Ligation. n = 5. 1 site: Egypt.

Key findings

Safety

Follow-up duration and efficacy and safety data are not provided.

Who this may help

The source did not state who this applies to in practice.

Plain-language summary

This is an active registry record for a small, uncontrolled feasibility study of a novel endoscopic device with no reported results; it represents first-in-human exploratory work.

Study design

As stated by the source record.

MethodsPrimary outcome measure: Weight Loss (assessed at 3 months)

DesignInterventional, Single Group, Open label, Treatment purpose

PopulationObesity; age from 18 Years; to 65 Years

Sample size5

InterventionBand Ligation

Setting1 site: Egypt

Reported figures

Quoted from the source exactly as published.

Planned enrollment5

Primary outcome measureWeight Loss

Primary outcome timepoint3 months

Procedure duration30 min

Caveats

No results are reported in this registry record.
Study is single-arm with no control or comparator group.
Planned sample size of 5 is too small to support clinical inference.
Follow-up duration and efficacy and safety data are not provided.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

limited

Single-arm interventional device study; no comparator or control group.

Directness

moderate

Primary outcome is weight loss at 3 months, a clinically relevant endpoint.

Consistency

insufficient

No results reported; cannot assess consistency with prior evidence.

Risk of bias

insufficient

Registry record only; no methodology detail sufficient to assess bias risk.

Sample adequacy

insufficient

Planned enrollment 5 participants; underpowered for any inference.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT04431232). This is a study registration, not published results. Lead sponsor: El Katib Hospital. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 5 participants (ESTIMATED). Conditions: Obesity. Interventions: DEVICE: Endoscopic Band Ligation. Primary outcome measures: Weight Loss , 3 months. Brief summary: To the best of our knowledge, this is the first study to use endoscopic band ligation for weight loss. All ligatures will be performed in the gastric body starting at the distal body; 5 parallel rows, with the last one in the proximal body.The entire procedure can be completed in 30 min. Oxygen is used for endoscopic air insufflation.Endoscopy is performed using propofol for sedation.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

Endoscopic Band LigationObesityNCT04431232El Katib Hospital