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Life sciences · Observational Study
ClinicalTrials.gov · October 22, 2026
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Observational Study.
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Registry record from ClinicalTrials.gov (NCT05868135). This is a study registration, not published results. Lead sponsor: St. Olavs Hospital. Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 800 participants (ACTUAL). Conditions: Depression Moderate, Anxiety, Social, Panic Disorder. Interventions: BEHAVIORAL: eMeistring. Primary outcome measures: Depression severity , Pre treatment (T1), up to 14 weeks after treatment start (T2), six months after T2 (T3) and after two years (T4); Social phobia , Pre treatment (T1), up to 14 weeks after treatment start (T2), six months after T2 (T3) and after two years (T4); Panic disorder symptoms , Pre treatment (T1), up to 14 weeks after treatment start (T2), six months after T2 (T3) and after two years (T4). Brief summary: The goal of this observational multicentre study is to address the effectiveness and cost-effectiveness of providing a therapist guided internet based cognitive behavioural therapy (ICBT) for common mental disorders in a routine healthcare setting. Main research questions is 1) What is the effectiveness of guided internet based treatment for moderate depression, panic disorder and social anxiety disorder across clinics in routine care? 2) What is the cost-effectiveness of guided internet based treatment for moderate depression, panic disorder and social anxiety disorder across clinics? 3) Who benefits from guided internet-delivered treatment? 4) What are the predictors of drop-out from guided internet based treatment? 5) To what extent does user experiences of guided internet based treatment influence adherence and effectiveness? Participants will receive up to nine guided ICBT sessions (modules) and answer questionnaires covering symptoms severity, health related quality of life, work and social ability, user satisfaction and medication. All questionnaires are part of the standard patient follow up routines in the four treatment locations participating in the study. Analytical approach is to compare locations/clinics and subgroups of patients.