Life sciences · Journal article
Jaimc Journal of Allama Iqbal Medical College · September 14, 2026
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AbstractBackground and Objective: Metabolic syndrome is characterized by central obesity, deranged lipid profile,high blood pressure and abnormally high levels of blood sugar. It is an independent risk factor forcardiovascular disease. Systemic Lupus Erythematosus (SLE) is an autoimmune disease that can affectjoints, skin, brain, lungs, kidneys, and blood vessels. The extent to which metabolic syndrome is frequent inour population is less known. The objective of this study was to assess the frequency of metabolic syndromeamongst SLE patients.Methods: This cross-sectional study was undertaken in a public sector tertiary care hospital of Lahore fromFebruary 2021 through August 2021, including 110 confirmed SLE cases. After institutional approval andtaking an informed consent, blood pressure, fasting and random blood sugar levels and fasting lipid profilewere measured. Central obesity was assessed using waist circumference. Data were transferred to SPSS 21for descriptive and inferential analyses. Frequencies were determined using numbers and percentages.Results: Of 110 SLE patients, 14 (12.3%) were males and 96 (87.7%) were females. Mean age of SLEpatients was 42.9± 9.9 years. Mean BMI was 28.7±4.7 kg/m2. The frequency of metabolic syndrome instudied SLE patients was 37/110 (33.6%).Conclusion: Systemic lupus erythematosus patients had abnormally high serum triglyceride and cholesterollevels, diabetes mellitus, central obesity, high levels of fasting plasma glucose and hypertension. Therefore,one-third of SLE patients may have metabolic syndrome in our population.Key Words: Dyslipidemia, Frequency, Metabolic Syndrome, Systemic Lupus Erythematosus.