Loading
Life sciences · Journal article
Technium Biochemmed · October 23, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Journal article.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
What is missing. This record has no bottom line, key findings, reported figures, evidence dimensions. That is a gap in the analysis, not a judgement about the study.
Abstract. Introduction: Human Immunodeficiency Virus (HIV) still represents a major public health issue, which concerns 19.315 patients from Romania, in 2025, according to the National Institute of Infectious Diseases "Dr. Matei Balș". The pathology associated with HIV is diverse due to the ability of HIV to decrease the number of CD4 cells, affecting the immune system and providing an opportunity for opportunistic pathogens to enter the human body. The introduction of ART has transformed HIV infection into a chronic disease that allows people living with HIV to live a long life, giving them the chance to have a seronegative child by providing the mother with an antiretroviral regimen during pregnancy. Objective: This review aims to highlight the evolution of HIV in Romania, with concerns such as treatment, people's behaviour in sexual interactions, routes of transmission and epidemiology. Materials and Methods: Relevant studies were identified via PubMed, Scopus and Google Scholar using a combination of the following keywords, including HIV Romania, ART resistance, HIV genetics, HIV structure and HIV mutation. Results: The HIV-1 subtype F1 is the most common in Romania, even though in Europe the most common subtype is B. The majority of the new cumulated HIV/AIDS cases (133) in 2025 occured in Bucharest, which was home to 4627 patients with HIV or AIDS, from the 672 new cumulative HIV/AIDS cases that were reported from first January 2025 to 31 December 2025. New cumulative HIV/AIDS cases reported in 2025 are more often found in male patients (80%). Switching from oral ART to long-lasting injections with cabotegravir/rilpivirine or lencapavir may improve adherence and the quality of life. Latest INSTIs are recommended due to favourable safety profiles, their high genetic barriers to resistance and the ability to achieve and maintain viral suppression. Conclusion: This disease is hard to manage by the Romanian health system due to high-risk sexual behaviours, and the use of dating applications that may facilitate the formation of extensive sexual networks, however, the relationship between use and the main route of transmission of HIV, represented by heterosexual and homosexual sexual contact, needs to be evaluated through epidemiological studies.