Life sciences · Preprint
arXiv · September 25, 2026
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Compressing a trained model yields a family of deployment candidates, and under domain shift the most compressed one need not be the one to deploy. We study selection over such a family, with candidates and teacher fixed and target labels absent or scarce. Two findings organize the label-free case. Minimum teacher distortion behaves almost as a constant rule, selecting the same eight-bit, per-channel, unclipped configuration in every run, which does not minimize empirical target cross-entropy. Established estimators divide sharply: in the overconfident-collapse regime of the CNN families, confidence-based estimators order the family close to backwards, and the diagnostics that identify it need the labels the setting denies, while output-distribution estimators match the teacher-relative anchor and on one architecture beat it. Distortion is nonetheless stable, so a supervised term can move selection away from it. Combining the two, we give exact quadratic identities for a canonical quadratic analogue of the family. We also show that under symmetric corruption the label-dependent part of a criterion linear in the label indicator is multiplied by one common factor whenever its coefficient sums are candidate-invariant, a class holding teacher contrasts and accuracy but not cross-entropy. These characterize the score's components without bounding selection regret. Across one hundred and thirty-four candidate families, one per independently trained convolutional or Vision Transformer teacher, anchoring reduces mean regret at the smallest label budget in every setting, an advantage that fades beyond twenty-five labels.